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861448-89-7

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861448-89-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 861448-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,4,4 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 861448-89:
(8*8)+(7*6)+(6*1)+(5*4)+(4*4)+(3*8)+(2*8)+(1*9)=197
197 % 10 = 7
So 861448-89-7 is a valid CAS Registry Number.

861448-89-7Downstream Products

861448-89-7Relevant articles and documents

Development of an enabling route to PF-00610355: A novel inhaled β2-adrenoreceptor agonist

De Koning, Pieter D.,Gladwell, Iain R.,Moses, Ian B.,Panesar, Maninder S.,Pettman, Alan J.,Thomson, Nicholas M.

, p. 1247 - 1255 (2011)

The initial route used to prepare PF-00610355 (8) for early clinical development is described. Through careful choice of solvent, an efficient, telescoped route to carboxylic acid 23 was developed, affording this late-stage intermediate in 80% yield over 4 steps. Deprotection of 23 to give sodium salt 24a and coupling with amine 6·HCl afforded the desired API. Effective synthetic routes to two of the starting materials, chiral bromide 1 and amine 6, are also described.

Sulfonamide derivatives for the treatment of diseases

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Page/Page column 18-19, (2008/06/13)

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in

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