861691-37-4

Basic information

• Product Name: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• Synonyms: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one;2''-O-beta-L-Galactopyranosylorientin;2"-O-beta-L-galactopyranosylorientin;2"-O-β-L-Galorientin;Orientin-2''-O-β-L-galactoside;2'-O-β-L-galactopyranosylorientin;Orientin 2''-galactoside
• CAS NO: 861691-37-4
• Molecular Formula: C27H30O16
• Molecular Weight: 610.52
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 861691-37-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 218-220℃
• Boiling Point: 988.9±65.0 °C(Predicted)
• Appearance: /
• Density: 1.87
• PKA: 6.19±0.40(Predicted)
• CAS DataBase Reference: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(861691-37-4)
• EPA Substance Registry System: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(861691-37-4)

Safety Data

• Hazardous Substances Data: 861691-37-4(Hazardous Substances Data)

Usage

Description

2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one is a complex flavonoid compound characterized by its multiple phenolic hydroxyl groups and sugar moieties. It is a natural product derived from various fruits and vegetables, known for its potent antioxidant properties and potential health benefits.

Uses

Used in Pharmaceutical Development:
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one is used as a pharmaceutical candidate for its anti-inflammatory, anti-cancer, and anti-diabetic properties. Its intricate structure and biological activities make it a promising agent for the development of new drugs targeting various health conditions.
Used in Nutritional Supplements:
In the health and wellness industry, 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one is used as a key ingredient in nutritional supplements for its antioxidant and health-promoting effects. It can be incorporated into formulations to support overall health and well-being.
Used in Functional Foods:
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one is also used in the development of functional foods, where it can be incorporated into food products to enhance their nutritional value and provide additional health benefits. Its antioxidant properties can contribute to the prevention of oxidative stress and support overall health.

Upstream product

• 133-89-1 UDP-glucose 
• 7480-94-6 Luteolin-8-C-glucoside 
• 2956-16-3 uridine 5'-diphospho-D-galactose 

Relevant articles and documents

Characterization of a Highly Selective 2″- O-Galactosyltransferase from Trollius chinensis and Structure-Guided Engineering for Improving UDP-Glucose Selectivity

A novel 2″-O-galactosyltransferase TcOGT4 was discovered from Trollius chinensis. TcOGT4 could regio-specifically catalyze 2″-O-galactosylation of 17 flavone 8-C-β-d-glucosides and shows high preference for UDP-Gal. Molecular docking indicated that Pro361 may play a key role in sugar donor selectivity, and the P361W mutant exhibited significantly enhanced selectivity toward UDP-Glc. A total of 21 products including 17 new compounds were obtained, and 5 of them showed potent COX-2 inhibitory activities. TcOGT4 is the first reported 2″-O-galactosyltransferase for flavone C-glycosides, and could be a powerful biocatalyst to synthesize bioactive flavone glycosides.