861701-99-7

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 668421-78-1 (2R,3S,6S,7R)-7-benzyloxy-9-(t-butyldimethylsiloxy)-1-(t-butyldiphenylsiloxy)-3-(p-methoxybenzyloxy)-2,6-dimethyl-cis-4-nonene 
• 668421-79-2 (3R,4S,7S,8R)-3-benzyloxy-9-(t-butyldiphenylsiloxy)-7-(p-methoxybenzyloxy)-4,8-dimethyl-cis-5-nonenoic acid 
• 861699-24-3 (3R,4S,7S,8R)-3-benzyloxy-9-(t-butyldiphenylsiloxy)-7-(p-methoxybenzyloxy)-4,8-dimethyl-cis-5-nonen-1-ol 
• 668421-68-9 (3R,4S,7S,8R)-3-benzyloxy-9-(tert-butyldiphenylsiloxy)-4,8-dimethyl-7-hydroxynonanoic acid 
• 861700-68-7 (3R,4S,7S,8R)-3-benzyloxy-9-(t-butyldiphenylsiloxy)-7-hydroxy-4,8-dimethyl-cis-5-nonenoic acid 
• 861697-67-8 (2R,3S,6S,7R)-7-benzyloxy-9-(t-butyldimethylsiloxy)-3-(p-methoxybenzyloxy)-2,6-dimethyl-cis-4-nonen-1-ol 
• 668421-77-0 (3R,4S,7S,8R)-3-benzyloxy-1-(t-butyldimethylsiloxy)-7,9-[(R)-p-methoxybenzylidenedioxy]-4,8-dimethyl-cis-5-nonene 
• 861692-36-6 (2S,3R)-3,5-[(R)-benzylidenedioxy]-2-methylpentyl 4-methylbenzenesulfonate 
• 668421-71-4 ethyl (2S,3R)-3-hydroxy-5-(triisopropylsiloxy)-2-methyl-2-methylthiopentanoate 
• 668421-69-0 (3R,4R)-3-benzyloxy-1-(tert-butyldimethylsiloxy)-5-iodo-4-methylpentanol 
• 668421-72-5 ethyl (2S,3R)-3,5-[(R)-benzylidenedioxy]-2-methyl-2-methylthiopentanoate 
• 668421-73-6 ethyl (2R,3R)-3,5-[(R)-benzylidenedioxy]-2-methylpentanoate 
• 861693-85-8 (3R,4R)-3-benzyloxy-5-iodo-4-methylpentanol 

Downstream Products

• 668421-65-6 (3R,4S,7S,8R,13S)-3-benzyloxy-13-(t-butyldimethylsiloxy)-9-hydroxy-4,8,10,14-tetramethyl-(E)-10-pentadecen-7-olide 
• 861709-66-2 (3R,4S,7S,8S,13S)-3-benzyloxy-13-(t-butyldimethylsiloxy)-4,8,10,14-tetramethyl-9-oxo-(E)-10-pentadecen-7-olide 
• 861709-72-0 (3R,4S,7S,8S,13S)-3-benzyloxy-13-hydroxy-4,8,10,14-tetramethyl-9-oxo-(E)-10-pentadecen-7-olide 
• 668421-66-7 (3R,4S,7S,8R)-3-benzyloxy-9-oxo-4,8-dimethylnonan-7-olide 

Relevant academic research and scientific papers

Enantioselective total synthesis of octalactin a using asymmetric aldol reactions and a rapid lactonization to form a medium-sized ring

Octalactin A, an antitumor agent containing an eight-memhered lactone moiety, has been stereoselectively prepared by means of enantioselective aldol reactions of selected silyl enolates with achiral aldehydes, promoted by a chiral Sn11 complex.

Asymmetric total synthesis of octalactin B using a new and rapid lactonization

A method for the synthesis of octalactin B is established via a new and quite effective mixed-anhydride lactonization for the synthesis of an eight-membered ring moiety using 2-methyl-6-nitrobenzoic anhydride with DMAP. Both an optically active linear pre