86173-12-8

Upstream product

• 65827-57-8 1,2,6-tri-O-acetyl-3,4-di-O-benzyl-α-D-mannopyranose 
• 86172-81-8 (2R,3S,4S,5S,6S)-6-Benzyloxy-5-trityloxy-2-trityloxymethyl-tetrahydro-pyran-3,4-diol 
• 100-44-7 benzyl chloride 
• 100759-62-4 2,6-di-O-acetyl-3,4-di-O-benzyl-α-D-mannopyranosyl bromide 
• 100-51-6 benzyl alcohol 
• 108-24-7 acetic anhydride 
• 80859-30-9 benzyl 3,4-di-O-benzyl-α-D-mannopyranoside 

Downstream Products

• 94537-68-5 Benzyl-6-O-benzoyl-3,4-di-O-benzyl-α-D-mannopyranosid 
• 94537-67-4 Benzyl-6-O-acetyl-3,4-di-O-benzyl-α-D-mannopyranosid 
• 80859-30-9 benzyl 3,4-di-O-benzyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis and characterization of 6-O-β-lactosyl-α,β-D-mannopyranoses and 2,6-di-O-β-lactosyl-α,β-D-mannopyranoses. Synthesis and Binding of D-Galactose-terminated Ligands to Human and Rabbit Asialoglycoprotein Receptor. Part IV.

The reaction of 2,3,6,2',3',4',6'-hepta-O-acetyl-α-lactosyl bromide (4) and benzyl 3,4-di-O-benzyl-α-D-mannopyranoside (3) in the presence of mercury(II) cyanide in benzene-nitromethane produced benzyl 3,4-di-O-benzyl-2,6-bis-O-(2,3,6,2',3',4',6'-hepta-O-

SYNTHESE EINES N-ACETYLNEURAMINSAEURE-HALTIGEN SYNTHESEBLOCKS. KUPPLUNG ZUM N-ACETYLNEURAMINSAEURE-TETRASACCHARID MIT TRIMETHYLSILYLTRIFLAT

A trisaccharide synthetic block consisting of N-acetylneuraminic acid and lactosamine that allows general coupling reactions to other saccharide units was obtained.O-(Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-α- and -β-D-glycero-D-galacto-2-nonulopyranosylonate)-(2->6)-O-(2,3,4-tri-O-acetyl-β-D-galactopyranosyl)-(1->4)-1,3,6-tri-O-acetyl-2-desoxy-2-phthalimido-β-D-glucopyranose were used as glycosyl donors.In the presence of trimethylsilyltriflate, both compounds were converted into tetrasaccharides by reaction with derivatives of D-mannose unsubstituted at OH-2 representing the glycosyl acceptors.Removal of the protecting groups gave O-(5-acetamido-3,5-dideoxy-α- and -β-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->6)-O-β-D-galactopyranosyl-(1->4)-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->2)-D-mannopyranose, respectively.

Ditritylation of Methyl and Benzyl α-D-Gluco-, -Manno-, and -Galactopyranosides and Preparation of Their Partially Benzylated Derivatives

The ditritylation of methyl and benzyl α-D-gluco-, -manno-, and -galactopyranosides with trityl chloride in pyridine at 70 deg C proceeds in a regioselective manner to give the 2,6-ditrityl ethers of the glucosides, the 3,6-ones of the mannosides, and bot