86176-61-6Relevant academic research and scientific papers
Preparation of α-silyl- or α,α-bis(silyl)-substituted alkylcopper reagents and their synthetic use
Kondo, Junichi,Inoue, Atsushi,Ito, Yuki,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 3361 - 3369 (2007/10/03)
Treatment of chlorobis(methyldiphenylsilyl)methyllithium with various alkyl and aryl Grignard reagents and CuCN·2LiCl afforded 1,1- disilylalkylcopper species. The aerobic oxidation of the resulting copper reagents provided a variety of acylsilanes in good yields. Meanwhile, treatment of dichloro(methyldiphenylsilyl)methyllithum with Bu2CuLi·LiCN provided 1-cyano-1-silylalkylcopper species via consecutive double 1,2-migration of alkyl and cyano groups.
The Scope and Limitations of Intramolecular Radical Cyclizations of Acylsilanes with Alkyl, Aryl, and Vinyl Radicals
Chang, Sheng-Yueh,Jiaang, Weir-Torn,Cherng, Chaur-Donp,Tang, Kuo-Hsiang,Huang, Chih-Hao,Tsai, Yeun-Min
, p. 9089 - 9098 (2007/10/03)
5-Exo cyclizations of primary and secondary radicals with acylsilanes successfully give cyclopentyl silyl ethers. The corresponding 6-exo cyclizations are sensitive to changes of the size of silyl groups. Secondary radicals undergo 6-exo cyclizations with
Regioselectivity in and Annulation Reactions of Bis(trimethylsilyl) Enol Ethers with Acylsilane Dicarbonyl Dielectrophiles
Molander, Gary A.,Siedem, Christopher S.
, p. 130 - 138 (2007/10/02)
A number of 1,4- and 1,5-acylsilane dicarbonyl compounds were synthesized using Corey-Brook dithiane methods.These dicarbonyl substrates were annulated with the bis(trimethylsilyl) enol ether of methyl acetoacetate in the presence of TMSOTf, affording bic
