86177-06-2 Usage
Description
2-[(Ethylamino)methyl]-4-aminophenol Dihydrochloride is an organic compound that serves as an intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its ethylaminomethyl and aminophenol groups, which contribute to its reactivity and potential applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
2-[(Ethylamino)methyl]-4-aminophenol Dihydrochloride is used as a synthetic intermediate for the production of N-[4-[[4-alkoxy-3-[(dialkylamino)methyl]phenyl]amino]-2-pyrimidinyl]-N'-phenylguanidines and N-[4-[[4-alkoxy-3-[(dialkylamino)methyl]phenyl]amino]-2-pyrimidinyl]-N''-phenylguanidines. These compounds exhibit antifilarial activity, making them valuable in the development of treatments for filarial diseases, such as lymphatic filariasis and onchocerciasis.
Check Digit Verification of cas no
The CAS Registry Mumber 86177-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,1,7 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86177-06:
(7*8)+(6*6)+(5*1)+(4*7)+(3*7)+(2*0)+(1*6)=152
152 % 10 = 2
So 86177-06-2 is a valid CAS Registry Number.
86177-06-2Relevant articles and documents
Synthesis of stable isotope–labeled chloroquine and amodiaquine and their metabolites
Wu, Ruilian,Williams, Robert F.,Silks, L.A. “Pete”,Schmidt, Jurgen G.
, p. 230 - 248 (2019/05/24)
Anti-malaria drugs chloroquine and amodiaquine and their metabolites were synthesized to incorporate 13C and 15N starting from U-13C–labeled benzene to give M?+?7 isotopomers. Chloroquine and its metabolites were prepared
