86179-59-1

Basic information

• Product Name: 5-bromo-2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one
• Synonyms: 5-bromo-2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one
• CAS NO: 86179-59-1
• Molecular Weight: 303.196
• Mol File: 86179-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one(86179-59-1)
• EPA Substance Registry System: 5-bromo-2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one(86179-59-1)

Safety Data

• Hazardous Substances Data: 86179-59-1(Hazardous Substances Data)

Upstream product

• 37617-17-7 2-(6-methoxycarbonylhexyl)-cyclopentanone 

Relevant articles and documents

PRACTICAL SYNTHESIS OF 2-(6'-METHOXYCARBONYLHEXYL)CYCLOPENT-2-EN-1-ONE (PROSTAGLANDIN SYNTHON)

2-(6'-Methoxycarbonylhexyl)cyclopentanone was obtained by alkylation of the 2-(ethoxycarbonyl)cyclopentanone potassium salt with diethyl 5-bromopentylmalonate followed by acid cleavage of the obtained triester and esterification.Its bromination with copper bromide and dehydrobromination with collidine lead to 2-(6'-methoxycarbonylhexyl)cyclopent-2-en-1-one (a known prostaglandin synthon) with an overall yield of 28percent.The use of molecular bromine for bromination leads to the production of the 5-bromo analog of the synthon.