861843-76-7

Basic information

• Product Name: 1-(2,5-dimethoxy-phenylamino)-3,4-dihydro-naphthalene-2-carbaldehyde
• Synonyms: 1-(2,5-dimethoxy-phenylamino)-3,4-dihydro-naphthalene-2-carbaldehyde
• CAS NO: 861843-76-7
• Molecular Weight: 309.365
• Mol File: 861843-76-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2,5-dimethoxy-phenylamino)-3,4-dihydro-naphthalene-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-dimethoxy-phenylamino)-3,4-dihydro-naphthalene-2-carbaldehyde(861843-76-7)
• EPA Substance Registry System: 1-(2,5-dimethoxy-phenylamino)-3,4-dihydro-naphthalene-2-carbaldehyde(861843-76-7)

Safety Data

• Hazardous Substances Data: 861843-76-7(Hazardous Substances Data)

Upstream product

• 3262-03-1 1-chloro-2-formyl-3,4-dihydronaphthalene 
• 102-56-7 2,5-dimethoxyaniline 
• 117582-62-4 1-bromo-2-formyl-3,4-dihydronaphthalene 

Relevant articles and documents

Chemoselective arylamination of β-bromovinylaldehydes followed by acid catalyzed cyclization: a general method for polycyclic quinolines

A synthesis of polycyclic quinolines is described via palladium-catalyzed chemoselective arylamination of β-bromovinylaldehydes with aromatic amines followed by acid catalyzed cyclization.

Selective palladium-catalyzed amination of β-chloroacroleins by substituted anilines

β-Chloroacroleins can undergo a selective amination on their chloro position under palladium catalysis; in those conditions, no imine formation was observed. Their coupling with anilines carrying electron-donating or electron-withdrawing substituents proceeds in moderate to good yields and steric hindrance does not seem to be a limitation as o-substituted anilines react readily.