861853-90-9

Upstream product

• 177283-77-1 (4R,5R)-N,N'-dimethoxy-N,N',2,2-tetramethyl-1,3-dioxolane-4,5-dicarboxamide 
• 89980-68-7 3,4-dimethylphenylmagnesium bromide 
• 63126-29-4 (4R,5R)-2,2,N,N,N',N'-hexamethyl-1,3-dioxolane-4,5-dicarboxamide 

Downstream Products

• 861853-99-8 (4S,5S)-4,5-Bis-[(R)-(3,4-dimethyl-phenyl)-methoxy-methyl]-2,2-dimethyl-[1,3]dioxolane 
• 861854-02-6 (1R,2R,3R,4R)-1,4-Bis-(3,4-dimethyl-phenyl)-1,4-dimethoxy-butane-2,3-diol 

Relevant academic research and scientific papers

Nucleophilic addition reactions of 1,4-diketones derived from tartaric acid: Synthesis of TADDOL analogues

A systematic investigation of the reduction and Grignard reagents addition to 1,4-diketones derived from tartaric acid was carried out. It was found that the reduction proceeded with high selectivity using K-Selectride as the reducing agent; while Grignar

Asymmetric synthesis of α-methoxyarylacetic acid derivatives

Stereoselective synthesis of a series of 2-aryl-2-methoxyethanols was achieved from inexpensive chiral pool tartaric acid employing a diastereoselective reduction of a symmetrical 1,4-diaryldiketone as the key step. 2-Aryl-2-methoxyethanols were enantioselectively prepared in 80-90% yield