86186-39-2

Basic information

• Product Name: 3-(2'-methyl-3'-trimethylsilyl-2'-cyclopentene-1'-yl)-2-cyclohexen-1-one
• Synonyms: 3-(2'-methyl-3'-trimethylsilyl-2'-cyclopentene-1'-yl)-2-cyclohexen-1-one
• CAS NO: 86186-39-2
• Molecular Weight: 248.44
• Mol File: 86186-39-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2'-methyl-3'-trimethylsilyl-2'-cyclopentene-1'-yl)-2-cyclohexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2'-methyl-3'-trimethylsilyl-2'-cyclopentene-1'-yl)-2-cyclohexen-1-one(86186-39-2)
• EPA Substance Registry System: 3-(2'-methyl-3'-trimethylsilyl-2'-cyclopentene-1'-yl)-2-cyclohexen-1-one(86186-39-2)

Safety Data

• Hazardous Substances Data: 86186-39-2(Hazardous Substances Data)

Upstream product

• 40996-91-6 3-vinyl-cyclohex-2-enone 
• 74542-82-8 1-methyl-1-(trimethylsilyl)allene 

Relevant articles and documents

SCOPE AND STEREOCHEMICAL COURSE OF THE (TRIMETHYLSILYL)CYCLOPENTENE ANNULATION

A new, regiospecific annulation approach to highly substituted 5-membered carbocycles has been developed.The "TMS-cyclopentene annulation" involves the reaction of (trimethylsilyl)allenes with electrondeficient alkenes and alkynes in the presence of titanium tetrachloride to afford, in a single step, a functionalized and highly substituted TMS-cyclopentene derivative.Annulations employing α, β-unsaturated ketones proceed stereoselectively via suprafacial addition to the enone.Some useful transformations of the annulation products are also described; for example, treatment with K2CO3-methanol or HF in acetonitrile effects isomerization and desilylation yielding α, β-unsaturated ketones.