861882-16-8

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 597577-90-7 2,6-Bis-(4-chloro-phenyl)-piperidin-4-one 
• 3518-84-1 2,6-bis-(4-chloro-phenyl)-1-methyl-piperidin-4-one 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 1260866-45-2 3-{[2,6-bis(4-chlorophenyl)-1-methylpiperidin-4-ylidene]amino}-2-thioxo-imidazolidin-4-one 

Relevant academic research and scientific papers

Synthesis of some 2-Thioxo-imidazolidin-4-one derivatives and its antimicrobial activity

Series of newly prepared 3-{[2,6-bis(4-substituted phenyl)-1-methylpiperidin-4-ylidene] amino}-2-thioxo-imidazolidin-4-one derivatives (3a-3f) have been synthesized by the cyclization of compound (2a-2f), ethyl chloro acetate and fused sodium acetate. The

Synthesis and study of antibacterial and antifungal activities of novel 8-methyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones

Some novel spiropiperidinyl-1,2,4-triazolidin-3-thiones have been synthesized and studied for their antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa and antifungal activity against Candida albicans, Candida-6, Candida-51, Aspergillus niger and Aspergillus flavus. Compounds 30-32 exhibited potent in vitro antibacterial activity against E. coli and P. aeruginosa whereas the same set of compounds exerted potent in vitro antifungal activity against Candida-6, A. niger and A. flavus.