861882-87-3 Usage
Appearance
white solid
Use
antidiabetic agent
Function
reduces blood sugar levels
Mechanism of action
inhibits the enzyme aldose reductase, which is involved in the formation of sorbitol in the body
Potential applications
treatment of neuropathy and other complications associated with diabetes
Therapeutic potential
under investigation for its potential therapeutic effects in other conditions
Check Digit Verification of cas no
The CAS Registry Mumber 861882-87-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,8,8 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 861882-87:
(8*8)+(7*6)+(6*1)+(5*8)+(4*8)+(3*2)+(2*8)+(1*7)=213
213 % 10 = 3
So 861882-87-3 is a valid CAS Registry Number.
861882-87-3Relevant academic research and scientific papers
Structure-based design and synthesis of pyrazinones containing novel P 1 'side pocket' moieties as inhibitors of TF/VIIa
Schweitzer, Barbara A.,Neumann, William L.,Rahman, Hayat K.,Kusturin, Carrie L.,Sample, Kirby R.,Poda, Gennadiy I.,Kurumbail, Ravi G.,Stevens, Anna M.,Stegeman, Roderick A.,Stallings, William C.,South, Michael S.
, p. 3006 - 3011 (2007/10/03)
We describe the structure-based design, synthesis, and enzymatic activity of a series of substituted pyrazinones as inhibitors of the TF/VIIa complex. These inhibitors contain substituents meta to the P1 amidine designed to explore additional i
