861889-29-4

Upstream product

• 5994-87-6 diphenylphosphinamide 
• 861889-33-0 N-{1-[(4-methylphenyl)sulfonyl]-2-(trityloxy)ethyl}-P,P-diphenylphosphinamide 
• 861889-36-3 P,P-diphenyl-N-{1-[(trityloxy)methyl]propyl}phosphinamide 
• 861889-26-1 (S)-N-(1-hydroxybutan-2-yl)-P,P-diphenylphosphinic amide 

Downstream Products

• 861889-32-9 methyl 2-[(diphenylphosphoryl)amino]butanoate 

Relevant academic research and scientific papers

Enantioselective synthesis of β-amino alcohols and α-amino acids via a copper catalyzed addition of diorganozinc reagents to N-phosphinoylimines

Enantioenriched β-amino alcohols were prepared via an asymmetric addition of diethylzinc, catalyzed by the BozPHOS·Cu(I) complex, on in situ formed N-phosphinoylimines. The nature of the hydroxyl protecting groups was found to affect the enantioselectivities. Subsequent deprotection and oxidation of N-phosphinoyl β-amino alcohols afforded optically active α-amino acids (97% ee).