861896-82-4

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 20972-36-5 (E)-4-oxo-4-(p-tolyl)but-2-enoic acid 

Downstream Products

• 1273329-14-8 (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-(4-methylphenyl)prop-1-yl)dodecanamide 
• 1273329-04-6 (1R,3R)-3-amino-1-(4-methylphenyl)butane-1,4-diol acetate 
• 1213638-14-2 (1R,3R)-3-amino-1-(4-methylphenyl)butane-1,4-diol 
• 1273328-90-7 (1R,3R)-1-(4-methylphenyl)-3-((R)-1-phenylethylamino)butane-1,4-diol 
• 861896-85-7 (2R,4S)-4-hydroxy-4-(4-methylphenyl)-2-{[(1R)-1-phenylethyl]amino}butanoic acid 

Relevant academic research and scientific papers

Crystallization-induced asymmetric transformations (CIAT): Stereoconvergent acid-catalyzed lactonization of substituted 2-amino-4-aryl-4-hydroxybutanoic acids

Acid-catalyzed lactonization in dilute hydrochloric acid of N-substituted 2-amino-4-aryl-4-hydroxybutanoic acids with electron donating aryl substituents is stereoconvergent. The stereochemical outcome is controlled by the precipitation of little soluble