861965-65-3Relevant academic research and scientific papers
Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists
Wang, Xueqing,Bhatia, Pramila A.,Daanen, Jerome F.,Latsaw, Steve P.,Rohde, Jeffrey,Kolasa, Teodozyi,Hakeem, Ahmed A.,Matulenko, Mark A.,Nakane, Masaki,Uchic, Marie E.,Miller, Loan N.,Chang, Renjie,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.
, p. 4667 - 4678 (2007/10/03)
A series of 3-aryl piperidine analogs with 2-piperidinoalkylamino or 2-piperidinoalkyloxy fused bicyclic rings were prepared and found to be potent and efficacious human dopamine D4 agonists. The synthesis and structure-activity relationship (SAR) studies that led to the identification of these compounds are discussed.
Oximes and hydrazones that are useful in treating sexual dysfunction
-
Page/Page column 41, (2010/02/13)
The present invention relates to oximes and hydrazones of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
