861965-65-3

Basic information

• Product Name: 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one
• Synonyms: 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one
• CAS NO: 861965-65-3
• Molecular Weight: 318.415
• Mol File: 861965-65-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one(861965-65-3)
• EPA Substance Registry System: 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one(861965-65-3)

Safety Data

• Hazardous Substances Data: 861965-65-3(Hazardous Substances Data)

Upstream product

• 149108-74-7 5-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 630121-83-4 3-(thiazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 877168-33-7 5-(thiazol-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 630121-84-5 3-(thiazol-2-yl)piperidine 
• 347-93-3 3-chloro-4'-fluoropropiophenone 

Relevant articles and documents

Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists

A series of 3-aryl piperidine analogs with 2-piperidinoalkylamino or 2-piperidinoalkyloxy fused bicyclic rings were prepared and found to be potent and efficacious human dopamine D4 agonists. The synthesis and structure-activity relationship (SAR) studies that led to the identification of these compounds are discussed.