86209-44-1 Usage
Uses
Used in Pharmaceutical Industry:
2-Amino-4,6-bis(difluoromethoxy)pyrimidine is used as a research compound for its potential role in cancer treatment. Its unique molecular structure and functional groups contribute to its reactivity and safety profile, making it a valuable candidate for the development of new medicines.
Used in Research Settings:
2-Amino-4,6-bis(difluoromethoxy)pyrimidine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its precise properties, including reactivity and safety issues, are dictated by its molecular structure and particular functional groups, making it a crucial component in the advancement of scientific research.
Check Digit Verification of cas no
The CAS Registry Mumber 86209-44-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,0 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 86209-44:
(7*8)+(6*6)+(5*2)+(4*0)+(3*9)+(2*4)+(1*4)=141
141 % 10 = 1
So 86209-44-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H3F6N3O2/c7-5(8,9)16-2-1-3(15-4(13)14-2)17-6(10,11)12/h1H,(H2,13,14,15)
86209-44-1Relevant academic research and scientific papers
Process for producing fluoroalkoxyaminopyrimidines
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, (2008/06/13)
A novel process for producing fluoroalkoxyaminopyrimidines of the formula I STR1 wherein R is hydrogen, C1 -C4 -alkyl, C1 -C4 -alkoxy or benzyl, X is halogen, C1 -C4 -alkyl, C1 -C4 -alkoxy, C1 -C4 -haloalkyl, C1 -C4 -haloalkoxy, C1 -C4 -alkylamino or di-C1 -C4 -alkylamino, and T is hydrogen, chlorofluoromethyl, bromofluoromethyl, difluoromethyl or 1,2,2,2-tetrafluoroethyl, characterized in that a thiopyrimidine of the formula II STR2 wherein Y has the meaning given for X under the formula I or is hydroxyl, A is hydrogen, sodium, potassium or an equivalent of calcium or magnesium, and Q is C1 -C4 -alkyl, phenyl or benzyl, is reacted with difluorochloromethane, difluorobromomethane, tetrafluoroethylene, perfluoropropylene, trifluorobromoethylene or trifluorochloroethylene in the presence of a base; the resulting compound of the formula III STR3 is converted by oxidation into a compound of the formula IV STR4 wherein n is the number one or two; and this compound is treated with an amine of the formula V
