86209-44-1 Usage
General Description
2-Amino-4,6-bis(difluoromethoxy)pyrimidine is a specialized chemical compound belonging to the pyrimidine class, which is a basic structure found in many important biomolecules like nucleotides. The characteristics of this chemical derive from its unique structure that includes two amino groups and two difluoromethoxy groups attached to a pyrimidine ring. It is used primarily in research settings and plays a significant role in the pharmaceutical industry for developing medicine, especially for its possible relevance to cancer treatment. Its precise properties, including reactivity and safety issues, are dictated by its molecular structure and particular functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 86209-44-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,0 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 86209-44:
(7*8)+(6*6)+(5*2)+(4*0)+(3*9)+(2*4)+(1*4)=141
141 % 10 = 1
So 86209-44-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H3F6N3O2/c7-5(8,9)16-2-1-3(15-4(13)14-2)17-6(10,11)12/h1H,(H2,13,14,15)
86209-44-1Relevant articles and documents
Process for producing fluoroalkoxyaminopyrimidines
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, (2008/06/13)
A novel process for producing fluoroalkoxyaminopyrimidines of the formula I STR1 wherein R is hydrogen, C1 -C4 -alkyl, C1 -C4 -alkoxy or benzyl, X is halogen, C1 -C4 -alkyl, C1 -C4 -alkoxy, C1 -C4 -haloalkyl, C1 -C4 -haloalkoxy, C1 -C4 -alkylamino or di-C1 -C4 -alkylamino, and T is hydrogen, chlorofluoromethyl, bromofluoromethyl, difluoromethyl or 1,2,2,2-tetrafluoroethyl, characterized in that a thiopyrimidine of the formula II STR2 wherein Y has the meaning given for X under the formula I or is hydroxyl, A is hydrogen, sodium, potassium or an equivalent of calcium or magnesium, and Q is C1 -C4 -alkyl, phenyl or benzyl, is reacted with difluorochloromethane, difluorobromomethane, tetrafluoroethylene, perfluoropropylene, trifluorobromoethylene or trifluorochloroethylene in the presence of a base; the resulting compound of the formula III STR3 is converted by oxidation into a compound of the formula IV STR4 wherein n is the number one or two; and this compound is treated with an amine of the formula V