862122-95-0Relevant academic research and scientific papers
Monophosphine compound, transition metal complex thereof and production method of optically active compound using the complex as asymmetric catalyst
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Page/Page column 25-26, (2010/02/15)
The present invention provides a compound represented by the formula (I): wherein ring A is void or a benzene ring optionally having substituent(s), R1 and R2 are each independently a phenyl group optionally having substituent(s), a cyclohexyl group and the like, R3 and R4 are each independently a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group and the like, and X is a residue represented by —OR5 or —NHR6 wherein R5 and R6 are a lower alkyl group optionally having substituent(s), an aralkyl group optionally having substituent(s) and the like, a asymmetric transition metal complex containing the compound as a ligand and a production method of optically active compound using the complex as an asymmetric catalyst.
Catalytic, enantioselective, conjugate alkyne addition
Knoepfel, Thomas F.,Zarotti, Pablo,Ichikawa, Takashi,Carreira, Erick M.
, p. 9682 - 9683 (2007/10/03)
We document a copper-catalyzed, enantioselective, conjugate addition involving the direct use of a terminal acetylene, which undergoes in situ metalation. The addition reactions of phenylacetylene to Meldrum's acid derived acceptors take place in aqueous
