862123-01-1Relevant academic research and scientific papers
Catalytic, enantioselective, conjugate alkyne addition
Knoepfel, Thomas F.,Zarotti, Pablo,Ichikawa, Takashi,Carreira, Erick M.
, p. 9682 - 9683 (2005)
We document a copper-catalyzed, enantioselective, conjugate addition involving the direct use of a terminal acetylene, which undergoes in situ metalation. The addition reactions of phenylacetylene to Meldrum's acid derived acceptors take place in aqueous
Enantioselective Alkyne Conjugate Addition Enabled by Readily Tuned Atropisomeric P,N-Ligands
Mishra, Sourabh,Liu, Ji,Aponick, Aaron
supporting information, p. 3352 - 3355 (2017/03/15)
By the nature of its structure, the 5-membered chiral biaryl heterocyclic scaffold represents a departure from 6-membered P,N-ligands that facilitates tuning and enables ligand evolution to address issues of selectivity and reactivity. In this vein, the C
Monophosphine compound, transition metal complex thereof and production method of optically active compound using the complex as asymmetric catalyst
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Page/Page column 27-28, (2010/02/15)
The present invention provides a compound represented by the formula (I): wherein ring A is void or a benzene ring optionally having substituent(s), R1 and R2 are each independently a phenyl group optionally having substituent(s), a cyclohexyl group and the like, R3 and R4 are each independently a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group and the like, and X is a residue represented by —OR5 or —NHR6 wherein R5 and R6 are a lower alkyl group optionally having substituent(s), an aralkyl group optionally having substituent(s) and the like, a asymmetric transition metal complex containing the compound as a ligand and a production method of optically active compound using the complex as an asymmetric catalyst.
