86213-26-5Relevant academic research and scientific papers
Cu-Catalyzed direct cyanation of terminal alkynes with AMBN or AIBN as the cyanation reagent
Rong, Guangwei,Mao, Jincheng,Zheng, Yang,Yao, Ruwei,Xu, Xinfang
supporting information, p. 13822 - 13825 (2015/09/07)
A Cu-catalyzed direct cyanation of terminal alkynes was reported with broad substrate generality in moderate to high yield, and AMBN (azobisisoamylonitrile)/AIBN (azobisisobutyronitrile) were used as less toxic and effective cyanating sources in open air. Interestingly, addition products were selectively achieved as the major product under the same conditions in argon.
Copper mediated oxidative coupling between terminal alkynes and CuCN
Li, Yihang,Shi, Dunfa,Zhu, Pengqi,Jin, Hongxing,Li, Shuo,Mao, Feng,Shi, Wei
supporting information, p. 390 - 392 (2015/04/27)
A direct oxidative cross coupling between terminal alkynes and CuCN to form 1-cyanoalkynes was reported. FeCl3 was employed as the sole additive. The reaction could be carried out under mild conditions, with moderate to good yields.
Synthesis of Conjugated Alkynenitriles
Yalda, R,Rao, V. Subrahmanyeswara,Rao, Jampani Madhusundana
, p. 1046 - 1048 (2007/10/02)
The synthesis of 2-butynenitrile (7a), 3-(4-methoxyphenyl)-(7b)-, 3-(4-ethoxyphenyl)-(7c)-, 3-(4-nitrophenyl)-(7d)- and 3-(3,4,5-trimethoxyphenyl)-(7e)-propynenitriles by thermal decomposition of the corresponding acylcyanomethylenetriphenylphosphoranes (6a-e) is described.The ethoxycarbonylcyanomethylenetriphenylphosphorane (6f) under the same conditions does not give the alkynenitrile.Cleavage to triphenylphosphine oxide and acetylenic nitrile is the predominant fragmentation observed in the mass spectra of all the ylids.
