862159-03-3Relevant academic research and scientific papers
Lactones 23: Synthesis of cis-fused bicyclic hydroxy lactones with a p-menthane system
Dams, Iwona,Bialonska, Agata,Ciunik, Zbigniew,Wawrzenczyk, Czeslaw
, p. 2087 - 2097 (2007/10/03)
Enantiomeric pairs of cis-fused bicyclic hydroxy lactones with a p-menthane system were obtained in a several step synthesis from enantiomerically pure isomers of (+)-(R)- and (-)-(S)-pulegone. One-pot allyl-Claisen rearrangement of cis-pulegols, epoxidation of γ,δ-unsaturated p-nitrophenyl esters and acidic lactonization of epoxy esters are key synthetic steps. The structures of the compounds were confirmed by both spectroscopic and crystallographic methods.
