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86217-42-7

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86217-42-7 Usage

General Description

2-AMINO-2-(1-NAPHTHYL)ETHANOL, also known as 2-amino-2-naphthol, is a chemical compound with the molecular formula C14H13NO. It is a white to off-white crystalline powder that is soluble in water and organic solvents. 2-AMINO-2-(1-NAPHTHYL)ETHANOL is commonly used as a reagent in organic synthesis and as a building block in the production of various pharmaceuticals and dyes. It has also been studied for its potential therapeutic applications, including as an anti-inflammatory and analgesic agent. Additionally, 2-AMINO-2-(1-NAPHTHYL)ETHANOL has been investigated for its role in inhibiting amyloid fibril formation, which may have implications for the treatment of neurodegenerative diseases such as Alzheimer's.

Check Digit Verification of cas no

The CAS Registry Mumber 86217-42-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,1 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 86217-42:
(7*8)+(6*6)+(5*2)+(4*1)+(3*7)+(2*4)+(1*2)=137
137 % 10 = 7
So 86217-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO/c13-12(8-14)11-7-3-5-9-4-1-2-6-10(9)11/h1-7,12,14H,8,13H2

86217-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-2-naphthalen-1-ylethanol

1.2 Other means of identification

Product number -
Other names 1-Naphthaleneethanol,b-amino

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86217-42-7 SDS

86217-42-7Downstream Products

86217-42-7Relevant articles and documents

Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2

Welker, Armin,Kersten, Christian,Müller, Christin,Madhugiri, Ramakanth,Zimmer, Collin,Müller, Patrick,Zimmermann, Robert,Hammerschmidt, Stefan,Maus, Hannah,Ziebuhr, John,Sotriffer, Christoph,Schirmeister, Tanja

supporting information, p. 340 - 354 (2020/10/19)

Inhibition of coronavirus (CoV)-encoded papain-like cysteine proteases (PLpro) represents an attractive strategy to treat infections by these important human pathogens. Herein we report on structure-activity relationships (SAR) of the noncovalent active-site directed inhibitor (R)-5-amino-2-methyl-N-(1-(naphthalen-1-yl)ethyl) benzamide (2 b), which is known to bind into the S3 and S4 pockets of the SARS-CoV PLpro. Moreover, we report the discovery of isoindolines as a new class of potent PLpro inhibitors. The studies also provide a deeper understanding of the binding modes of this inhibitor class. Importantly, the inhibitors were also confirmed to inhibit SARS-CoV-2 replication in cell culture suggesting that, due to the high structural similarities of the target proteases, inhibitors identified against SARS-CoV PLpro are valuable starting points for the development of new pan-coronaviral inhibitors.

Highly efficient asymmetric access to 1-azaspiro[4.4]nonane skeleton

Planas, Lo?c,Pérard-Viret, Jo?lle,Royer, Jacques,Selkti, Mohamed,Thomas, Alain

, p. 1629 - 1632 (2007/10/03)

Vinylogous Mukaiyama aldol type reaction of chiral non-racemic silyloxypyrroles followed by acidic treatment affords an efficient asymmetric access to 1-azaspiro[4.4]nonanes in high diastereoisomeric excess (up to 79%).

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