862188-37-2 Usage
Chemical structure
A derivative of 1,3-propanediol with a tert-butylphenyl group attached to the molecule.
Functional groups
Contains a diol functional group (two hydroxyl groups) and a tert-butylphenyl group.
Molecular weight
Approximately 214.32 g/mol
Appearance
Likely a colorless to pale yellow liquid or solid, depending on the temperature and concentration.
Solubility
Soluble in organic solvents such as ethanol, methanol, and acetone. May have limited solubility in water.
Boiling point
The exact boiling point is not provided, but it is expected to be higher than that of 1,3-propanediol due to the presence of the bulky tert-butylphenyl group.
Melting point
The exact melting point is not provided, but it is expected to be lower than that of 1,3-propanediol due to the presence of the bulky tert-butylphenyl group.
Density
The exact density is not provided, but it is expected to be higher than that of 1,3-propanediol due to the presence of the bulky tert-butylphenyl group.
Viscosity
The exact viscosity is not provided, but it is expected to be higher than that of 1,3-propanediol due to the presence of the bulky tert-butylphenyl group.
Reactivity
May react with other organic compounds through reactions such as esterification, etherification, and substitution reactions.
Applications
Potentially used as a building block for the synthesis of specialized polymers or other organic compounds with unique properties.
Safety
The safety profile of 1,3-Propanediol, 1-[4-(1,1-dimethylethyl)phenyl]- is not provided, but it is important to consider the potential hazards associated with the parent compound (1,3-propanediol) and the added tert-butylphenyl group.
Storage
Should be stored in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Keep away from incompatible substances and use appropriate containment and personal protective equipment during handling.
Environmental impact
The environmental impact of 1,3-Propanediol, 1-[4-(1,1-dimethylethyl)phenyl]- is not provided, but it is important to consider the potential effects of the parent compound (1,3-propanediol) and the added tert-butylphenyl group on the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 862188-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,1,8 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 862188-37:
(8*8)+(7*6)+(6*2)+(5*1)+(4*8)+(3*8)+(2*3)+(1*7)=192
192 % 10 = 2
So 862188-37-2 is a valid CAS Registry Number.
862188-37-2Relevant academic research and scientific papers
Lewis Base-Promoted Ring-Opening 1,3-Dioxygenation of Unactivated Cyclopropanes Using a Hypervalent Iodine Reagent
Gieuw, Matthew H.,Ke, Zhihai,Yeung, Ying-Yeung
supporting information, p. 3782 - 3786 (2018/03/13)
A facile and effective system has been developed for the regio- and chemoselective ring-opening/electrophilic functionalization of cyclopropanes through C?C bond activation by [bis(trifluoroacetoxy)iodo]benzene with the aid of the Lewis basic promoter p-toluenesulfonamide. The p-toluenesulfonamide-promoted system works well for a wide range of cyclopropanes, resulting in the formation of 1,3-diol products in good yields and regioselectivity.
Pradefovir: A prodrug that targets adefovir to the liver for the treatment of hepatitis B
Reddy, K. Raja,Matelich, Michael C.,Ugarkar, Bheemarao G.,Gómez-Galeno, Jorge E.,DaRe, Jay,Ollis, Kristin,Sun, Zhili,Craigo, William,Colby, Timothy J.,Fujitaki, James M.,Boyer, Serge H.,Van Poelje, Paul D.,Erion, Mark D.
, p. 666 - 676 (2008/09/19)
Adefovir dipivoxil, a marketed drug for the treatment of hepatitis B, is dosed at submaximally efficacious doses because of renal toxicity. In an effort to improve the therapeutic index of adefovir, 1-aryl-1,3-propanyl prodrugs were synthesized with the r
