862195-40-2Relevant academic research and scientific papers
Synthesis of aib-containing cyclopeftides via the 'azirine/oxazolone method'
Dannecker-Doerig, Ingeborg,Linden, Anthony,Heimgartner, Heinz
, p. 901 - 925 (2009)
The cyclic pentapeptide cyclo[Gly-Phe(2Me)-Aib-Aib-Gly], containing three α,α-disubstituted α-amino acids, was prepared by cyclization of H-Gly-Phe(2Me)-Aib-Aib-Gly-OH with diphenyl phosporazidate (DPPA) in 60% yield. The synthesis of the linear precursor
