86222-94-8Relevant academic research and scientific papers
Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics
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, (2008/06/13)
The present invention concerns substituted heterocyclic phenoxyamines having the following formula: STR1 their pharmacologically acceptable acid salts, their quaternary ammonium salts, their N-oxides, their levorotatory and dextrorotatory isomers and the processes for the preparation thereof. In the above formula: m=0 or 2 n=0 or 2 provided that m+n=2 A represents hydrogen, a lower alkoxy or lower alkenyloxy group, X represents a halogen, R represents hydrogen or a saturated or unsaturated aliphatic and/or cyclic hydrocarbon radical such as in particular lower alkyl, lower alkenyl, cycloalkyl and cycloalkyl-alkyl, cycloalkenyl and cycloalkenyl-alkyl. The compounds of the invention are useful as local anaesthetics.
