86238-54-2Relevant academic research and scientific papers
Chirality Transfer in Stereoselective Synthesis. A Highly Stereoselective Synthesis of Optically Active Vitamin E Side Chains
Koreeda, Masato,Brown, Lindsey
, p. 2122 - 2124 (2007/10/02)
Employing the Carroll reaction as a means of chirality transfer, a highly efficient, stereochemically controlled, and generally applicable synthesis of optically active 1,5-dimethylated acyclic chains has been developed; as an example, the synthesis of the optically active C-15 vitamin E side chains 7a and 7b from (+)-pulegone in 12.6percent and 11.7percent overall yields, respectively, is described.
