86239-01-2

Basic information

• Product Name: 4-BroMoMethyl-3-fluorobenzoic acid ethyl ester
• Synonyms: 4-BroMoMethyl-3-fluorobenzoic acid ethyl ester;Ethyl 4-(bromomethyl)-3-fluorobenzoate
• CAS NO: 86239-01-2
• Molecular Formula: C₁₀H₁₀BrFO₂
• Molecular Weight: 261.0876032
• Mol File: 86239-01-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-BroMoMethyl-3-fluorobenzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMoMethyl-3-fluorobenzoic acid ethyl ester(86239-01-2)
• EPA Substance Registry System: 4-BroMoMethyl-3-fluorobenzoic acid ethyl ester(86239-01-2)

Safety Data

• Hazardous Substances Data: 86239-01-2(Hazardous Substances Data)

Upstream product

• 350-28-7 3-fluoro-4-methyl-benzoic acid 
• 86239-00-1 ethyl 3-fluoro-4-methylbenzoate 

Downstream Products

• 1197295-13-8 [4-(ethoxycarbonyl)-2-fluorobenzyl](triphenyl)phosphonium bromide 
• 86238-86-0 diethyl (4-carbethoxy-2-fluorobenzyl)phosphonate 
• 86238-93-9 (E)-3-(4-carbethoxy-2-fluorophenyl)-2-methylpropenal 
• 86238-93-9 (Z)-3-(4-carbethoxy-2-fluorophenyl)-2-methylpropenal 
• 86238-75-7 (E)-1-(4-carbethoxy-2-fluorophenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene 
• 86238-76-8 (E)-1-(4-carboxy-2-fluorophenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene 
• 86238-88-2 1-(4-carbethoxy-2-fluorophenyl)-2-methylpropene 
• 895519-98-9 3-fluoro-4-(4-methylpiperazin-1-ylmethyl)-benzoic acid 
• 880874-01-1 3-fluoro-4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid ethyl ester 

Relevant articles and documents

BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR

The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof.

Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors

A series of 3-substituted benzamide derivatives structurally related to STI-571 (imatinib mesylate), a Bcr-Abl tyrosine kinase inhibitor used to treat chronic myeloid leukemia (CML), was prepared and evaluated for antiproliferative activity against the Bc

Aromatic Retinoic Acid Analogues. 2. Synthesis and Pharmacological Activity

Aromatic analogues of (E)-1-(4-carboxyphenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene (1b) and its ethyl ester (1a) were synthesized as potential chemopreventive agents for the treatment of epithelial cancer and such skin diseases as psoriasis and cystic acne.The phenyl ring of 1 was replaced by 2-fluorophenyl, 2-methoxyphenyl, thienyl, furanyl, and pyridyl groups.The 1-fluorobutadiene analogue of 1 was also synthesized.With exception for the furanyl analogue, these compounds demonstrated good activity in reversing keratinization in hamster tracheal organ culture and in inhibiting the induction of ornithine decarboxylase in mouse epidermis by a tumor promoter.