862457-83-8

Basic information

• Product Name: 5-(4-fluorophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione
• Synonyms: 5-(4-fluorophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione
• CAS NO: 862457-83-8
• Molecular Weight: 314.34
• Mol File: 862457-83-8.mol

Chemical Properties

• CAS DataBase Reference: 5-(4-fluorophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-fluorophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(862457-83-8)
• EPA Substance Registry System: 5-(4-fluorophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-8(9H)-thione(862457-83-8)

Safety Data

• Hazardous Substances Data: 862457-83-8(Hazardous Substances Data)

Upstream product

• 197368-47-1 1-(4-fluorophenyl)-7,8-methylenedioxy-3,5-dihydro-2,3-benzodiazepin-4(4H)-one 
• 6006-82-2 3,4-methylenedioxyphenethyl alcohol 
• 2861-28-1 1,3-benzodioxole-5-acetic acid 
• 862457-81-6 [6-(4-fluoro-benzoyl)-benzo[1,3]dioxol-5-yl]-acetic acid 
• 862457-79-2 5-(4-fluoro-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isochromene 

Relevant articles and documents

Novel α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: Chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration

Under pathophysiological conditions, α-amino-3-hydroxy-5-methyl-4- isoxazole propionate (AMPA) receptor activation is considered to play a key role in several disorders of the central nervous system. In the search for AMPA receptor antagonists, the synthe

CONDENSED 2,3-BENZODIAZEPINE DERIVATIVES AND THIER USE AS AMPA-RECEPTOR INHIBITORS

Compounds of formula I are described, their production and use in pharmaceutical agents.