862458-01-3Relevant academic research and scientific papers
PIPERIDINE DERIVATIVES AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7
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, (2018/05/16)
The present invention concerns the identification of inhibitors of ubiquitin specific protease 7 (USP7), and methods of use thereof.
PHARMACEUTICAL COMPOUNDS
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Page/Page column 90, (2018/02/28)
The present invention relates to compounds of Formula (I) that are useful as inhibitors of the activity of the ubiquitin specific protease USP19. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in therapy.
Stereocontrolled synthesis of β-difluoromethylated materials
Nihei, Takashi,Iwai, Noritaka,Matsuda, Tomoko,Kitazume, Tomoya
, p. 5912 - 5915 (2007/10/03)
Investigation of synthetic routes for regio- and stereocontrolled fluorinated materials with a difluoromethyl group, using ethyl bromodifluoroacetate as a starting material, is described. In particular, (E)-difluoromethylated trisubstituted olefins were p
