862494-58-4

Upstream product

• 1246637-52-4 C₂₀H₃₀N₂O₂ 

Downstream Products

• 862494-38-0 (S)-(1-cyclohexylmethyl-pyrrolidin-2-ylmethyl)-quinolin-3-ylmethyl-amine 
• 862494-37-9 N-(S)-(1-cyclohexylmethyl-pyrrolidin-2-ylmethyl)-3,4-dimethoxy-N-naphthalen-2-ylmethyl-benzamide 

Relevant academic research and scientific papers

Substituted arylamides

Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer.

Methods and compositions for modulating angiogenesis

The present invention provides method and compositions for modulating angiogenesis.

INHIBITORS OF HUMAN TUMOR-EXPRESSED CCXCKR2

Pharmaceutical compositions containing organic compounds or salts thereof that serve as modulators for the SDF-1 or I-TAC chemokines are disclosed. The compounds and compositions are useful in the treatment of cancer, especially in the inhibition of cancer proliferation, growth, and metastasis. Methods of interfering with SDF-1 and/or I-TAC binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the present invention are also disclosed.