86255-82-5

Upstream product

• 16184-79-5 3-acetoxy-2,2-dimethyl-1-propanal 
• 86255-80-3 Acetic acid 2-[(2S,3R)-1-(2,4-dimethoxy-benzyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-4-oxo-azetidin-2-yl]-2-methyl-propyl ester 
• 86269-26-3 Acetic acid 2-[(2R,3S)-3-(benzyl-benzyloxycarbonyl-amino)-1-(2,4-dimethoxy-benzyl)-4-oxo-azetidin-2-yl]-2-methyl-propyl ester 
• 86255-79-0 Acetic acid 3-[(Z)-2,4-dimethoxy-benzylimino]-2,2-dimethyl-propyl ester 
• 86255-81-4 Acetic acid 2-[(2R,3S)-1-(2,4-dimethoxy-benzyl)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-2-yl]-2-methyl-propyl ester 
• 86255-81-4 Acetic acid 2-[(2R,3R)-1-(2,4-dimethoxy-benzyl)-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-2-yl]-2-methyl-propyl ester 

Relevant academic research and scientific papers

STEREOSPECIFIC AND NON-HAZARDOUS SYNTHESIS OF CIS AND TRANS-3-PHENOXYACETAMIDO-4-(2-ACETOXY-1,1-DIMETHYLETHYL)-AZETIDIN-2-ONES KEY INTERMEDIATES FOR THE SYNTHESIS OF 6-AMIDO-1,1-DIMETHYL-CARBAPEN-2-EMS

The title compounds have been prepared by a four-step sequence from 3-acetoxy-2,2-dimethyl-1-propanal and a novel non-hazardous and stereospecific route to cis-3-amido-azetidin-2-ones by the use of N-benzyl-2-carbobenzoxyglycine is described.