86257-64-9Relevant academic research and scientific papers
Medicaments, vicinal dihydroxyalkylxanthines contained therein, processes for the preparation of these xanthine compounds and intermediate products suitable for these
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, (2008/06/13)
Compounds of the formula STR1 wherein one of the radicals R1, R2 or R3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the ω,ω-1 or ω-1,ω-2 positions and the two other radicals represent straight-chain or branched alkyl groups having up to 12 C atoms in the position of R1 and R3 and up to 4 C atoms in the position of R2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.
