862647-15-2

Upstream product

• 3542-14-1 3,3-diphenylpropene 
• 947-91-1 Diphenylacetaldehyde 
• 15701-83-4 1,1-diphenyl-2,3-epoxy-propan 
• 862647-11-8 (2S)-3,3-diphenylpropane-1,2-diol 
• 862647-10-7 (2S)-2-benzhydryloxirane 
• 862647-13-0 (2R)-1,1-diphenylpent-4-en-2-ol 
• 106-95-6 allyl bromide 

Downstream Products

• 862647-21-0 (1S,4R,6R)-4-benzhydryl-3,7-dioxabicyclo[4.1.0]heptane 
• 862647-20-9 (1R,4R,6S)-4-benzhydryl-3,7-dioxabicyclo[4.1.0]heptane 
• 862647-17-4 (2R)-2-benzhydryl-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

TRI-SUBSTITUED 2-BENZHYDRYL-5-BENZLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES

Novel 3,6-disubstituted pyrans, optionally with a further substituent at the 4-position, are monoamine reuptake inhibitors with activity profiles of anti- depressants.

Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner

In our structure-activity relationship study on 3,6-disubstituted pyran derivatives, we have carried out asymmetric synthesis and biological characterization of trisubstituted (2S,4R,5R)-2-benzhydryl-5- benzylaminotetrahydropyran-4-ol and (3S,4R,6S)-6-ben