86268-06-6 Usage
General Description
(3-methyl-2,3-diphenyl-3,4-dihydroquinoxalin-1(2H)-yl)(phenyl)methanone, also known as BAY 13-9952, is a chemical compound with potential pharmaceutical applications. It is a quinoxaline derivative that has been studied for its potential in treating a variety of medical conditions, including cancer and neurological disorders. Quinoxaline derivatives are known for their diverse biological activities, including antibacterial, antiviral, antifungal, antitumor, and anti-inflammatory properties. BAY 13-9952 has been specifically investigated for its potential as a tyrosine kinase inhibitor, which could make it useful in the treatment of certain types of cancer. Its specific mechanisms of action and potential therapeutic uses continue to be explored through preclinical and clinical research.
Check Digit Verification of cas no
The CAS Registry Mumber 86268-06-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,6 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86268-06:
(7*8)+(6*6)+(5*2)+(4*6)+(3*8)+(2*0)+(1*6)=156
156 % 10 = 6
So 86268-06-6 is a valid CAS Registry Number.
86268-06-6Relevant articles and documents
Action d'organolithiens sur la methyl-2 quinoxaline. Etude de la reactivite des adduits
Mettey, Yvette,Vierfond, Jean-Michel,Thal, Claude,Miocque, Marcel
, p. 133 - 137 (2007/10/02)
The action of organolithium reagents such as phenyllithium or n-butyllithium on 2-methylquinoxaline gave lithiation of the methyl group which upon reaction with electrophiles produce side chain alkenyl derivatives.On the other hand organolithium reagents react with the quinoxaline azomethine bond to give 1-lithio-2-alkyl(or aryl)-3-methylquinoxalines which can be further lithiated on the methyl group to give 2-alkyl(or aryl)-3-alkenylquinoxaline derivatives.The adducts can be condensed with electrophiles such as benzonitrile or methyl benzoate but only methyl benzoate leads to N condensed derivatives.Furthermore substituted 1,2,3,4-tetraquinoxalines are available via the above lithio intermediates.
