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NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone, is a chemical compound that is a deuterated analog of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). It is a beige solid and is commonly found in smokeless tobacco products. Due to its presence in tobacco products and its carcinogenic properties, it is likely to play a significant role in the development of various types of cancer.

86270-92-0

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86270-92-0 Usage

Uses

Used in Cancer Research:
NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone, is used as a research compound for studying the etiology of cancers associated with tobacco use. Its presence in smokeless tobacco products makes it an important factor in the development of lung, oral cavity, and pancreatic cancers. Researchers use NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone to investigate the mechanisms of carcinogenesis and to develop potential strategies for cancer prevention and treatment.
Used in Toxicology Studies:
As a deuterated analog of NNK, NNK-d3 is used in toxicology studies to understand the metabolic pathways and toxic effects of TSNA compounds in the body. This knowledge can help in assessing the risks associated with tobacco product use and in the development of safer alternatives.
Used in Analytical Chemistry:
NNK-d3, 4-(Methyl-d3-nitrosoamino)-1-(3-pyridinyl)-1-butanone, can be used as an internal standard in analytical chemistry for the quantification of its non-deuterated counterpart, NNK, in tobacco products and biological samples. The use of deuterated internal standards improves the accuracy and precision of analytical measurements, making it a valuable tool in quality control and regulatory compliance.

Check Digit Verification of cas no

The CAS Registry Mumber 86270-92-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,2,7 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 86270-92:
(7*8)+(6*6)+(5*2)+(4*7)+(3*0)+(2*9)+(1*2)=150
150 % 10 = 0
So 86270-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N3O2/c1-13(12-15)7-3-5-10(14)9-4-2-6-11-8-9/h2,4,6,8H,3,5,7H2,1H3/i1D3

86270-92-0 Well-known Company Product Price

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  • (49578)  4-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanone  analytical standard

  • 86270-92-0

  • 49578-2MG

  • 2,861.82CNY

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86270-92-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-oxo-4-pyridin-3-ylbutyl)-N-(trideuteriomethyl)nitrous amide

1.2 Other means of identification

Product number -
Other names NNK-d3

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86270-92-0 SDS

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