86272-41-5Relevant academic research and scientific papers
Asymmetric organocatalytic oxy-Michael addition of alcohols to α,β-unsaturated aldehydes
Kano, Taichi,Tanaka, Youhei,Maruoka, Keiji
, p. 8658 - 8664 (2007)
A 1,4-addition of alcohols to α,β-unsaturated aldehydes was found to be efficiently promoted by biphenyldiamine-based catalyst 3?without formation of the acetals. An asymmetric variant of this reaction has also been performed by designing a novel axially
1,3-Asymmetric Induction in Diastereoselective Allylations of Chiral N-Tosyl Imines
Fettinger, James C.,Gutierrez, David A.,Lo, Anna,Shaw, Jared T.,Toth-Williams, Garrett
, (2022/02/07)
Lewis acid mediated allylations of β-alkoxy N-tosyl imines using allyltrimethylsilane lead to 3-alkoxy homoallylic N-tosyl amines with anti-selectivity. Two methods of Cu(OTf)2-mediated allylations are reported herein, demonstrating that diastereoselectiv
Organocatalytic oxy-Michael addition of alcohols to α,β-unsaturated aldehydes
Kano, Taichi,Tanaka, Youhei,Maruoka, Keiji
, p. 3039 - 3041 (2007/10/03)
1,4-Addition of alcohols to α,β-unsaturated aldehydes was found to be efficiently promoted by biphenyldiamine-based catalyst 3 without formation of the acetals.
Concentration effects in chelation controlled reactions
Springer,Springer, James B.,DeBoard,Deboard, Julie,Corcoran,Corcoran, Robert C.
, p. 8733 - 8736 (2007/10/02)
The diastereoselectivities of addition reactions of allyltrimethylsilane to an α-benzyloxyaldehyde were found to be relatively insensitive to the amount of added TiCl4, and to the absolute concentration of the 1:1 aldehyde/TiCl4 complex. In contrast, diastereoselectivities of similar additions to a structurally related β-benzyloxyaldehyde were highly dependent on these variables.
