862723-42-0

Basic information

• Product Name: INDAZOLE-5-BORONIC ACID PINACOL ESTER
• Synonyms: 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE;1H-INDAZOLE-5-BORONIC ACID PINACOL ESTER;INDAZOLE-5-BORONIC ACID PINACOL ESTER;Indazole-5-boronic acid p...;5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole;1H-Indazole, 5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole, 2-(1H-Indazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1H-Indazole-5-boronic acid pinacol ester 95%
• CAS NO: 862723-42-0
• Molecular Formula: C₁₃H₁₇BN₂O₂
• Molecular Weight: 244.1
• Mol File: 862723-42-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 404.123 °C at 760 mmHg
• Flash Point: 198.207 °C
• Appearance: /
• Density: 1.154 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 14.01±0.40(Predicted)
• CAS DataBase Reference: INDAZOLE-5-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: INDAZOLE-5-BORONIC ACID PINACOL ESTER(862723-42-0)
• EPA Substance Registry System: INDAZOLE-5-BORONIC ACID PINACOL ESTER(862723-42-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 862723-42-0(Hazardous Substances Data)

Usage

General Description

Indazole-5-boronic acid pinacol ester is a chemical compound that belongs to the class of boronic acid esters. It is a derivative of indazole, a heterocyclic aromatic organic compound. INDAZOLE-5-BORONIC ACID PINACOL ESTER has been studied for its potential applications in medicinal chemistry, particularly as a building block for the synthesis of pharmaceutical compounds. It has also been investigated for its potential use in various catalytic processes. Indazole-5-boronic acid pinacol ester is a valuable tool for chemists and researchers working in the fields of drug discovery, organic synthesis, and catalysis. Its unique structure and reactivity make it a promising candidate for the development of new chemical and pharmaceutical products.

InChI:InChI=1/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-5-6-11-9(7-10)8-15-16-11/h5-8H,1-4H3,(H,15,16)

Upstream product

• 465529-55-9 5-bromo-2H-indazole 
• 73183-34-3 bis(pinacol)diborane 
• 53857-57-1 5-bromo-1H-indazole 

Downstream Products

• 2009273-67-8 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridyl]phenol 

Relevant articles and documents

IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR

The present invention relates to the compound of formula (I) and salts, stereoisomers, tautomers, isotopologues,or N-oxides thereof. The present invention is further concerned with the use of such a compound or salt, stereoisomer, tautomer, isotopologues,or N-oxide thereof as medicament and a pharmaceutical composition comprising said compound.

Heterocyclic compound with Wnt signal path inhibitory activity and application thereof

The invention provides a heterocyclic compound with Wnt signal path inhibitory activity. The heterocyclic compound and chemically acceptable salt, isotope, isomer and a crystal structure thereof are provided with a structure shown as the general formula I (see the formula in the description). The invention further provides application of the heterocyclic compound with the Wnt signal path inhibitory activity. The heterocyclic compound with the Wnt signal path inhibitory activity serves as effective antagonist of a Wnt signal path, and can be used for treating or preventing diseases caused by abnormity of the Wnt signal path.

HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.