862729-13-3

Basic information

• Product Name: 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
• Synonyms: 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine;7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, 5-iodo-7-Methyl-
• CAS NO: 862729-13-3
• Molecular Formula: C₇H₇IN₄
• Molecular Weight: 274.06175
• Mol File: 862729-13-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine(862729-13-3)
• EPA Substance Registry System: 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine(862729-13-3)

Safety Data

• Hazardous Substances Data: 862729-13-3(Hazardous Substances Data)

Usage

General Description

5-Iodo-7-Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound with potential pharmaceutical applications. It is a derivative of the pyrimidine molecule, containing an iodine atom and a methyl group attached to the seventh carbon atom. It is classified as an amine due to the presence of an amino group. 5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine may have biological activity related to its structure and properties, which makes it a potential candidate for drug development. Further research and testing are necessary to fully understand its pharmacological effects and potential therapeutic applications.

Upstream product

• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 3680-71-5 Allopurinol 
• 123148-78-7 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 
• 1500-85-2 7-deazaadenine 
• 163622-50-2 4-amino-5-iodo-7H-pyrrolo[2,3‐d]pyrimidine 
• 74-88-4 methyl iodide 
• 833481-37-1 4-chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 1391053-27-2 1,1-dimethylethyl 5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indole-1-carboxylate 

Relevant articles and documents

Method for synthesizing 4 -chloropyrropyrimidine compound (by machine translation)

The invention relates to a synthesis method of 4 -lopyrrolopyrimidine compound, which comprises the following steps: mixing 4 -hydroxypyrrolopyrimidine, phosphorus oxychloride and organic base in a temperature range &at;timetimewise and removing excess ethanol to obtain 3 - 7-amino-4 -iodopyrrolopyrimidine; thirdly, dissolving the product 4 -amino-4 -methyl pyrrolopyrimidine in DMF at room temperature and then drying and concentrating 4 -aminopyrrolopyridine. 4 -aminopyrimidine is dissolved in dichloromethane and then subjected to a heat preservation reaction to get -5 -aminopyrrolopyrimidine; and the mixture is dried to remove the solid insoluble matter and is dried and concentrated to yield 12 hours-aminopyrroyrimidine after the heat preservation reaction is carried out; and the solvent is evaporated to remove the solid insoluble matter and is dried and concentrated to remove the solid insoluble matter 4 -5 -7. (by machine translation)

N-(SUBSTITUTED-PHENYL)-SULFONAMIDE DERIVATIVES AS KINASE INHIBITORS

The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.

Kinase antagonists

The present invention provides novel compounds that are antagonists of PI3 kinase, PI3 kinase and tryosine kinase, PI3Kinase and mTOR, or PI3Kinase, mTOR and tryosine kinase.