862735-81-7

Upstream product

• 862735-92-0 dimethyl(phenyl)(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-yn-1-yl)silane 
• 6089-04-9 3-(tetrahydropyran-2'-yloxy)propyne 
• 768-33-2 phenyldimethylsilyl chloride 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 126361-99-7 (Z)-3-(dimethyl-phenyl-silanyl)-prop-2-en-1-ol 
• 1407797-83-4 (R)-6-(dimethylphenylsilyl)-7-octen-1-yl pivalate 
• 1407797-72-1 (Z)-1-dimethylphenysilyl-3-chloro-1-pentene 
• 1407797-81-2 (R)-dimethylphenyl(1-undecen-3-yl)silane 
• 1407797-91-4 C₁₉H₃₄Si 
• 1407797-82-3 (R)-[8-(1,3-dioxan-2-yl)-1-octen-3-yl]dimethylphenylsilane 

Relevant academic research and scientific papers

Copper-catalyzed enantioselective allylic substitution with alkylboranes

The first catalytic enantioselective allylic substitution reaction with alkylboron compounds has been achieved. The reaction between alkyl-9-BBN reagents and primary allylic chlorides proceeded with excellent γ-selectivities and high enantioselectivities under catalysis of a Cu(I)-DTBM-SEGPHOS system. The protocol produces terminal alkenes with an allylic stereogenic center branched with functionalized sp3-alkyl groups. The reaction with a γ-silicon-substituted allyl chloride affords an efficient strategy for the enantioselective synthesis of functionalized α-stereogenic chiral allylsilanes.

A convenient multigram synthesis of highly enantioenriched methyl 3-silylglycidates

A multigram scale synthesis of the four stereoisomers of methyl 3-silylglycidates (epoxysilanes) with high enantiopurity is described. Key reactions include a Sharpless asymmetric epoxidation (SAE) of a trans-vinylsilane and an enzymatic resolution of a r

Synthesis and [4 + 2]-annulation of enantioenriched (Z)-crotylsilanes: Preparation of the C1-C13 fragment of bistramide A

(Chemical Equation Presented) New chiral crotylsilanes that bear a (Z)-olefin geometry were synthesized in high enantiopurity. The reagents participate in [4 + 2]-annulations with aldehydes to give stereochemically complementary pyrans (relative to (E)-crotylsilanes) bearing 2,6-cis-5,6-cis and 2,6-trans-5,6-cis relationships of peripheral functionalities. A stereoselective synthesis of the C1-C13 fragment of bistramide A is also described highlighting this annulation strategy.