862828-08-8Relevant academic research and scientific papers
NON-NATURAL AMINO ACIDS AND NEUROTENSIN ANALOGUES THEREOF
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Page/Page column 74, (2010/11/27)
This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino N,N dimeth
NON-NATURAL AMINO ACIDS
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Page/Page column 61, (2010/02/15)
This invention relates to non-natural desamino alkyl amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino, alpha methyl N,N dimethyl homolysine residue.
Asymmetric synthesis of ω-bromo-2(S)-methyl acids as precursors for novel arginine, lysine, and mercapto residues
Hadden, M. Kyle,Kokko, Kyle P.,Dix, Thomas A.
, p. 1675 - 1680 (2007/10/03)
A series of ω-bromo-2(S)-methyl acids has been synthesized as precursors of novel arginine (Arg), lysine (Lys), and mercapto analogues. These intermediates contain α-methyl groups and are designed to mask the N-terminal amine when incorporated in pharmaceutically relevant peptides. Copyright Taylor & Francis, Inc.
