862839-00-7

Upstream product

• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 64152-76-7 methyl (S)-2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-4-methylpentanoate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 862839-09-6 (S)-2-((S)-2-Acryloylamino-3-phenyl-propionylamino)-4-methyl-pentanoic acid 3-bromo-benzylamide 

Relevant academic research and scientific papers

Synthesis of small cyclic peptides constrained with 3-(3-aminomethylphenyl) propionic acid linkers using free radical-mediated macrocyclization

In this letter, we report that small peptides (di- and tri-) having a 3-bromobenzyl group at the C-termini and an acryloyl group at the N-termini undergo an efficient Bu3SnH-AIBN mediated intramolecular free radical cyclization to afford cyclic