862893-81-0

Basic information

• Product Name: 2-(2,4,6-Trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c][1,2,4]triazol-4-ylium chloride
• Synonyms: 2-(2,4,6-Trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c][1,2,4]triazol-4-ylium chloride;2-Mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazol-4-iuM chloride 97%;6,7-Dihydro-2-(2,4,6-trimethylphenyl)-5H-pyrrolo[2,1-c]-1,2,4-triazolium chloride, 95%
• CAS NO: 862893-81-0
• Molecular Formula: C₁₄H₁₈N₃*Cl
• Molecular Weight: 263.76582
• Mol File: 862893-81-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 200-205°C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-(2,4,6-Trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c][1,2,4]triazol-4-ylium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4,6-Trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c][1,2,4]triazol-4-ylium chloride(862893-81-0)
• EPA Substance Registry System: 2-(2,4,6-Trimethyl-phenyl)-2,5,6,7-tetrahydro-pyrrolo[2,1-c][1,2,4]triazol-4-ylium chloride(862893-81-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 862893-81-0(Hazardous Substances Data)

Usage

Uses

Catalyst for:Intermolecular hydroacylation of cyclopropenesCrossed acyloin condensationsDomino ring-opening redox amidation Knoevenagel condensationClaisen rearrangementLewis acid- and N-heterocyclic carbene-catalyzed cyclocondensation reactionBode catalyst for enantioselective cyclizations

InChI:InChI=1/C14H18N3.ClH/c1-10-7-11(2)14(12(3)8-10)17-9-16-6-4-5-13(16)15-17;/h7-9H,4-6H2,1-3H3;1H/q+1;/p-1

Upstream product

• 5264-35-7 2-methoxy-1-pyrroline 
• 24006-09-5 mesitylhydrazine hydrochloride 
• 122-51-0 orthoformic acid triethyl ester 
• 955103-17-0 2-mesityl-1-(pyrrolidin-2-ylidene)hydrazinium chloride 

Relevant articles and documents

N-heterocyclic carbene-catalyzed annulation of α-cyano-1,4-diketones with ynals

In this paper, the first stereoselective annulation reaction between r-cyano-1,4-diketones and ynals, mediated by catalytic amounts of a triazolium salt precatalyst and cocatalytic amounts of a weak carboxylate base, is disclosed. The title transformation proceeds smoothly under mild reaction conditions and generates three contiguous stereogenic centers, one of which is a quaternary acetal carbon. This reaction tolerates a wide variety of electronically distinct substituents on both reaction partners and affords privileged bicyclic scaffolds in 61-90% isolated yields and with up to 20:1 diastereomeric preference.

ENANTIOSELECTVE REACTIONS CATALYZED BY CHIRAL TRIAZOLIUM SALTS

This invention provides a convenient method for converting imines and other electrophiles into heterocyclic ring systems. The process does not require the use of metallic reagents, and is catalyzed by an organic heterocyclic carbene catalyst. Accordingly,