86299-58-3

Upstream product

• 108908-49-2 (5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid 
• 17356-08-0 thiourea 
• 108908-46-9 p-nitrobenzyl chloroacetate 
• 108908-48-1 (Z)-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid 
• 108908-47-0 tert-butyl (Z)-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyrate 

Relevant academic research and scientific papers

Aminothiazole substituted penicillins and antibacterial compositions thereof

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: STR1 wherein R1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.

4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production

Disclosed are compounds of the general formula: STR1 wherein R1 is a hydrogen atom or a lower alkyl group and R2 is a hydrogen atom or an ester residue, said derivative having the (3S,4S)-configuration; and pharmaceutically acceptable salts and esters thereof. The compounds have antimicrobial and/or β-lactamase-inhibitory activity and are of value as drugs for human beings and domesticated animals.