86301-87-3Relevant academic research and scientific papers
A CONVENIENT REDUCTION OF ALKYLATED TOSYLMETHYL ISOCYANIDES: APPLICATIONS FOR THE SYNTHESIS OF NATURAL PRODUCTS
Yadav, J. S.,Reddy, P. Satyanarayana,Joshi, Bhalchandra V.
, p. 7243 - 7254 (2007/10/02)
A convenient and simple method for the reduction of mono- and dialkylated tosylmethyl isocyanides with lithium in liquid ammonia to corresponding hydrocarbons is described.The utility of this methodology adopted in the synthesis of tricos-9Z-ene (7g), a sex pheromone of common house fly, (-)-1S,5R,7S-exo-brevicomin (17), an antipode of sex pheromone of Western pine beetle and (4S,5S)-5-hydroxy-4-decanolide (L-factor, 19), a proposed autoregulator for leukaemomycin biosynthesis.
