863028-79-9

Basic information

• Product Name: ethyl 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylate
• Synonyms: ethyl 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylate
• CAS NO: 863028-79-9
• Molecular Weight: 321.763
• Mol File: 863028-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylate(863028-79-9)
• EPA Substance Registry System: ethyl 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylate(863028-79-9)

Safety Data

• Hazardous Substances Data: 863028-79-9(Hazardous Substances Data)

Upstream product

• 51940-64-8 ethyl 2,4-dichloropyrimidine-5-carboxylate 
• 621-33-0 m-phenetidine 

Downstream Products

• 863028-89-1 2-(1H-benzotriazol-1-yloxy)-4-(3-ethoxyanilino)pyrimidine-5-carboxamide 
• 863028-84-6 2-chloro-4-(3-ethoxyanilino)pyrimidine-5-carboxylic acid 

Relevant articles and documents

Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives

Spleen tyrosine kinase (Syk) is a non-receptor-type tyrosine kinase which mediates diverse responses in haematopoietic cells. Therefore, Syk is an attractive therapeutic target, and in a study of Syk inhibitors as potentially new therapeutic agents, we di