863222-46-2

Upstream product

• 863222-48-4 (3E,2'R,3'S,4'Z,6'R,7'S)-4-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-5-(tert-butyldimethylsilyloxy)-2-(trimethylsilyloxy)pent-3-enenitrile 
• 863222-66-6 (2R,3S,2'R,3'S,4'Z,6'R,7'S)-4-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-5-(tert-butyldimethylsilyloxy)-2,3-epoxypentanol 
• 863222-62-2 (2E,2'R,3'S,4'Z,6'R,7'S)-3-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-4-(tert-butyldimethylsilyloxy)-2-butenol 
• 863222-49-5 methyl (2E,2'R,3'S,4'Z,6'R,7'S)-3-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-4-(tert-butyldimethylsilyloxy)-2-butenoate 
• 863222-65-5 (2E,2'R,3'S,4'Z,6'R,7'S)-4-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-5-(tert-butyldimethylsilyloxy)-2-pentenol 
• 863222-47-3 (2E,2'R,3'S,4'Z,6'R,7'S)-4-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-5-(tert-butyldimethylsilyloxy)pent-2-enenitrile 
• 863222-63-3 (2E,2'R,3'S,4'Z,6'R,7'S)-3-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-4-(tert-butyldimethylsilyloxy)-2-butenal 
• 863222-64-4 (2E,2'R,3'S,4'Z,6'R,7'S)-4-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-5-(tert-butyldimethylsilyloxy)-2-pentenal 
• 863222-61-1 (2R,3S,4Z,6R,7S)-2-allyl-6-benzyloxy-7-benzyloxymethyl-3-(4-methoxybenzyloxy)-2,3,6,7-tetrahydrooxepin 
• 863222-60-0 (2R,3S,4Z,6R,7S)-{6-benzyloxy-7-benzyloxymethyl-3-(4-methoxybenzyloxy)-2,3,6,7-tetrahydrooxepin-2-yl}ethanal 
• 863222-50-8 (2R,3S,4Z,6R,7S)-2-allyl-6-benzyloxy-7-benzyloxymethyl-2,3,6,7-tetrahydrooxepin-3-ol 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 863222-68-8 (3S,2'R,3'S,4'Z,6'R,7'S)-2-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}hex-5-en-1,3-diol 
• 863222-67-7 (3S,2'R,3'S,4'Z,6'R,7'S)-2-{(2'-allyl-6'-benzyloxy-7'-benzyloxymethyl-2',3',6',7'-tetrahydrooxepin-3'-yl)oxy}-1-(tert-butyldimethylsilyloxy)hex-5-en-3-ol 

Relevant academic research and scientific papers

Synthesis of the EF-ring segment of ciguatoxin CTX1B based on novel regioselective reduction of unsaturated cyanohydrins and ring-closing olefin metathesis

Aiming at a convergent total synthesis of ciguatoxin CTX1B, its EF-ring segment has been synthesized. During the synthesis, a novel method for the construction of branched ethers, based on regioselective reduction of γ-alkoxy β,γ-unsaturated α-silyloxy ni