863225-69-8Relevant academic research and scientific papers
Facile one-pot synthesis of BINOL- and H8-BINOL-based aryl phosphites and their use in palladium catalysed asymmetric allylation
Gavrilov, Konstantin N.,Lyubimov, Sergey E.,Petrovskii, Pavel V.,Zheglov, Sergey V.,Safronov, Anton S.,Skazov, Roman S.,Davankov, Vadim A.
, p. 10514 - 10520 (2005)
Novel P-monodentate aryl phosphite ligands have been synthesised in one step from (R)-BINOL, (R)-H8-BINOL and (R)-H8-3,3′- dibromo-BINOL. With the new aryl phosphites, up to 86% ee was observed in the asymmetric Pd-catalysed aminatio
Pd-catalyzed asymmetric allylation with a novel C2-symmetric bisphosphinite ligand: 3R,3′R-bis(diphenylphosphinoxy)-6,6,6′,6′-tetramethyl-2S, 2′S-di-4H-pyran
Zhang, Ruzhou,Yu, Libing,Xu, Li,Wang, Zhiqin,Ding, Kuiling
, p. 7659 - 7662 (2007/10/03)
A novel C2-symmetric chiral bisphosphinite ligand, 3R,3′R-bis(diphenylphosphinoxy)-6,6,6′,6′-tetramethyl-2S, 2′S-di-4H-pyran, was synthesized from D-mannitol and examined for palladium-catalyzed asymmetric allylic substitution. Under the optimized conditions, the allylation product can be obtained in up to 91.2% ee.
