863248-27-5

Upstream product

• 773874-06-9 methyl 2,3-difluoro-4-methylbenzoate 

Downstream Products

• 1073543-79-9 4-(4-Bromo-2-butyl-5-formyl-imidazol-1-ylmethyl)-2,3-difluorobenzoic acid methyl ester 
• 1429647-43-7 4-((4-chloro-N-(2-hydroxycyclohexyl)phenylsulfonamido)methyl)-2,3-difluorobenzoic acid 
• 1429647-47-1 4-((4-chloro-N-(2,2-difluorocyclohexyl)phenylsulfonamido)methyl)benzoic acid 
• 1429647-76-6 methyl 4-((4-chloro-N-cyclohexylphenylsulfonamido)methyl)-2,3-difluorobenzoate 
• 1372175-49-9 (S)-methyl 4-((4-chloro-N-(1-phenylpropyl)phenylsulfonamido)methyl)-2,3-difluorobenzoate 

Relevant academic research and scientific papers

ANTIVIRAL COMPOUNDS AND USE THEREOF

The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.

Dual-acting antihypertensive agents

The invention is directed to compounds having the formula: wherein: Ar, r, Y, Z, Q, W, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

FXR AGONISTS

Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.