863301-40-0Relevant academic research and scientific papers
Enantioselective Friedel-Crafts type addition of indoles to nitro-olefins using a chiral hydrogen-bonding catalyst - Synthesis of optically active tetrahydro-β-carbolines
Zhuang, Wei,Hazell, Rita G.,Jorgensen, Karl Anker
, p. 2566 - 2571 (2005)
The enantioselective Friedel-Crafts addition of indoles to nitro-olefins using chiral hydrogen-bonding bis-sulfonamides as the catalysts has been developed. The reactions, in the presence of only 2 mol% catalyst, generally proceed in high yields and with
