863308-63-8

Upstream product

• 863308-61-6 5-bromo-7-(2-deoxy-β-D-erythro-pentofuranosyl)-4-(dimethylaminomethylidene)-7H-pyrazolo[3,4-d][1,2,3]triazine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 863308-47-8 4-amino-5-bromo-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrazolo[3,4-d][1,2,3]triazine 
• 863308-54-7 9-bromo-7-(2-deoxy-β-D-erythro-pentofuranosyl)imidazo[1,2-c]-7H-pyrazolo[4,3-e]pyrimidine 
• 863308-58-1 9-bromo-7-(2-deoxy-β-D-erythro-pentofuranosyl)-imidazo[1,2-c]-7H-pyrazolo[4,3-e][1,2,3]triazine 
• 908143-19-1 5-amino-3-bromo-1-(2-deoxy-β-D-erythro-pentofuranosyl)-4-(imidazol-2-yl)-1H-pyrazole 
• 200066-12-2 4-amino-3-bromo-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 

Relevant academic research and scientific papers

7-Deaza-2,8-diazaadenine containing oligonucleotides: Synthesis, ring opening and base pairing of 7-halogenated nucleosides

Oligonucleotides containing 7-bromo-7-deaza-2,8-diaza-2′- deoxyadenosine (3) and 5-amino-3-bromo-4-carbamoyl-1-(2′-deoxy-β-d- erythro-pentofuranosyl)pyrazole (4) were synthesized. Compound 3 was prepared from 7-bromo-8-aza-7-deaza-2′-deoxyadenosine (5) vi

7-Substituted 8-aza-7-deazapurines and 2,8-diaza-7-deaza-purines: Synthesis of nucleosides and oligonucleotides

7-Substituted 8-aza-7-deazaadenosines 1a-e were synthesized by Sonogashira cross coupling from the corresponding 7-iodo nucleoside in 36-79% yields. Starting from 7-bromo (or 7-iodo)-8-aza-7-deazaadenine, 2a,b were obtained by acid-catalyzed glycosylation