86331-38-6

Upstream product

• 5617-74-3 3-oxabicyclo[3.1.0]hexane-2,4-dione 
• 56613-80-0 D-2-phenylglycinol 

Downstream Products

• 86331-47-7 4-Hydroxy-3-((R)-2-hydroxy-1-phenyl-ethyl)-3-aza-bicyclo[3.1.0]hexan-2-one 
• 86331-52-4 2-Hydroxymethyl-cyclopropanecarboxylic acid ((R)-2-hydroxy-1-phenyl-ethyl)-amide 
• 86331-33-1 3-((R)-2-Hydroxy-1-phenyl-ethyl)-3-aza-bicyclo[3.1.0]hexane-2,4-dione 
• 86331-42-2 Acetic acid (R)-2-(2,4-dioxo-3-aza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-ethyl ester 

Relevant academic research and scientific papers

AN ASYMMETRIC SYNTHESIS OF BICYCLIC LACTONES AND ITS APPLICATION TO THE ASYMMETRIC SYNTHESIS OF (1R,3S)-CIS-CHRYSANTHEMIC ACID

Optically active bicyclic lactones are synthesized from imides, derived from (R)-(-)-2-amino-2-phenylethanol and meso-cyclic-1,2-cis-dicarboxylic acids, by successive treatment with sodium bis(2-methoxyethoxy)aluminum hydride and sodium borohydride, followed by acid hydrolysis.This reaction is successfully applied to the asymmetric synthesis of (1R,3S)-cis-chrysanthemic acid.